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[Japan] Cats: An era when cats have a lifespan of over 30 years due to AIM

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The life of a cat exceeds 30 years. Such an era is finally approaching. This is a big new drug development story that is very much talked about in Japan now. As a result of many years of research at the University of Tokyo, a treatment method for treating chronic kidney disease in cats has been established, and if it can be put into practical use, it will be possible for cats to have a lifespan of more than 30 years. All felines have weak kidneys that eventually lead to dysfunction and death, but it is likely that a radical cure for this will be established.

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AIM

The drug developed by the University of Tokyo in Japan is called AIM. Cats are genetically impaired in renal function earlier than other animals. The University of Tokyo has elucidated why this is because felines do not work with a protein called AIM that cleans garbage. AIM is an abbreviation for Apoptosis Inhibitor of Macrophage. It is said that one in three cats over the age of 15 will develop kidney disease. Kidney disease is greatly involved in the cause of death of cats. AIM sticks to the dust in the kidneys and informs them that there is dust, so macrophages can eat and clean the dust efficiently and cats are less likely to have kidney failure. It is predicted that if this treatment is possible, the average life expectancy of cats will exceed 30 years. The current average life expectancy is 15 years.

When will it be put into practical use?

The University of Tokyo development team, which is developing AIM, is aiming for practical application by 2023. He wants to be able to receive this treatment all over the world. Since cats are difficult to administer orally, it is likely that they will be powdered into powder and mixed with cat food to make it edible or injected. However, the specific prescription method has not been clarified yet.

Research support

In fact, this AIM treatment was delayed due to the influence of the coronavirus, and the research was suspended once in the summer of 2021. The Japanese who heard this made a total donation of about 200 million and were able to resume research. In other words, it is a new drug that is expected that much.

The longest life of a cat

The cat’s current longevity world record is 38 years old.

The world’s highest record is “Claim Puff” born in 1967 in Texas, USA. He lived to be 38 years old.

The second record is “Grandpa” born in 1964 in Texas, USA. The cat species lived in the Sphinx until the age of 34. It is a cat owned by the same owner as the claim puff.

There are other records in Canada, the United Kingdom and Australia over the age of 30.

Can you take care of the cat?

If a cat’s lifespan is extended to 30 years, the question arises as to whether humans can take care of it. However, humans are currently undergoing research on immortality and development of anti-aging drugs, and there is a possibility that they will be put to practical use in the United States or Japan. Humans are organisms that can divide cells up to the age of 125, but the current situation is that they cannot live to the limit age due to the increase in senescent cells. Therefore, research is continuing to prevent aging and rejuvenate by removing aging cells. Development is currently underway, including treatment methods using NMN, GLS1 inhibitors, and iPS cells, and rejuvenation has been demonstrated in non-clinical studies. Clinical trials are currently underway, and it is expected that it will take 5 to 10 years before it is put into practical use. It is said that if it is put into practical use, it will be a world that will live for up to about 120 years. Not only cats, but all living things are becoming longer-lived.

Introducing Japanese cat cafes

There are many cat cafes in Japan, and they are very popular with foreigners. I would like to introduce one of the cafes that I often go to.

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If you are interested, please go to Japan. Tickets and accommodations can be booked from the link below. It also supports other languages.

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